Raman spectroscopy, a non-destructive solution to the study of glass and its alteration

This paper presents the potential of Raman spectroscopy, a non-destructive technique which can be applied in-situ, for the analyses of glass and their alteration. Recent analytical developments are summarised for different glass composition and practical examples are given. The paper describes how to extract compositional information from the glass, first based on the spectra profile to distinguish rapidly alkali silicate from alkaline-earth alkali silicate and lead alkali silicate glass, then using the spectral decomposition and correlations to extract quantitative data. For alkali silicate glasses, that are most prone to alteration, the spectral characteristics are described to interpret the alteration process (selective leaching or dissolution of the glass) from the Raman spectra of the altered glass. These developments have greatly widened the potential of the technique and supplement well its ability to measure the thickness of the altered layer and identify the crystalline deposits

A vanadium / aspirin complex controlled release using a poly(ß-propiolactone) lm.

A delivery system for vanadiumwas developed using poly(¯-propiolactone)(P¯PL) lms. The release kinetics of a complex of vanadium (IV) with aspirin (VOAspi) was evaluated with lms prepared from polymers of differentmolecularweights, as well as with variable drug load. A sustained release of vanadium over 7 days was achieved. The drug release kinetics depends on contributions from two factors: (a) diffusion of the drug; and (b) erosion of the P¯PL lm. The experimental data at an early stage of release were tted with a diffusion model, which allowed determination of the diffusion coef cient of the drug. VOAspi does not show strong interaction with the polymer, as demonstrated by the low apparent partition coef cient (approximately 10¡2). UMR106 osteosarcoma cells were used as a model to evaluate the anticarcinogenic effects of the VOAspi released from the P¯PL lm. VOAspi–P¯PL lm inhibited cell proliferation in a dose-response manner and induced formation of approximately half of the thiobarbituric acid reactive substances (TBARS), an index of lipid peroxidation, compared to that with free VOAspi in solution. The unloaded P¯PL lm did not generate cytotoxicity, as evaluated by cell growth and TBARS. Thus, the polymer-embedded VOAspi retained the antiproliferative effects showing lower cytotoxicity than the free drug. Results with VOAspi–P¯PL lms suggest that this delivery system may have promising biomedical and therapeutic applications

Evaluación de las propiedades tecnológicas de sedimentos colmatantes de cuerpos lénticos ubicados al sudeste del área metropolitana de Buenos Aires. Estúdio preliminar para la formulación del Proyecto Productivo Inclusivo : Parque Ladrillero en el partido

Fil: Couyoupetrou, L.. Instituto de Recursos Minerales (INREMI). Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: Rolny, D.. Laboratorio de Tecnología y Gestión Habitacional (LATEC). Facultad de Arquitectura y Urbanismo. Universidad Nacional de La Plata; ArgentinaFil: Hurtado, Martín Adolfo. Instituto de Geomorfología y Suelos (IGS). Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: Etcheverry, Ricardo Oscar. Instituto de Recursos Minerales (INREMI). Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: Cremaschi, G.. Laboratorio de Tecnología y Gestión Habitacional (LATEC). Facultad de Arquitectura y Urbanismo. Universidad Nacional de La Plata; ArgentinaFil: Forte, Luis M.. Instituto de Geomorfología y Suelos (IGS). Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; Argentin

Pantothenate kinase-associated neurodegeneration: Novel mutations in the PANK2 gene in an argentinean young woman

Neurodegeneration with brain iron accumulation (NBIA) refers to a heterogeneous group of disorders.1–3 The pantothenate kinase-associated neurodegeneration (PKAN) is an autosomal recessive disorder caused by defective iron metabolism associated with mutations in the pantothenate kinase 2 (PANK2) gene on chromosome 20p13–p12.3.Fil: Gatto, Emilia Mabel. Instituto de Neurociencias Buenos Aires; ArgentinaFil: Etcheverry, Jose L.. Instituto de Neurociencias Buenos Aires; ArgentinaFil: Converso, Daniela Paola. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. Laboratorio de Metabolismo del Oxígeno; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bidinost, Carla. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. Laboratorio de Metabolismo del Oxígeno; ArgentinaFil: Rosa, Alberto Luis. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. Laboratorio de Metabolismo del Oxígeno; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentin

La andalucita de Mazan (Provincia de la Rioja) Y sus características tecnológicas

Han sido estudiadas las características mineralógicas y tecnológicas de la andalucita presente en pegmatitas del flanco suroccidental de la sierra de Ambato, provincia de La Rioja (minas "La Dichosa" y "Refrac "). Se señala su modo de yacencia, características ópticas, análisis químicos, difractogramas de Rayos X, espectrografía infrarroja, análisis térmico diferencial, así como ensayos tecnológicos que tipifican a este mineral en cuanto a usos industriales. Se sugiere un posible origen del mismo en los yacimientos tratados y finalmente se concluye que el material estudiado presenta aptitudes similares, para su utilización industrial a las de una muestra procedente de Sud Africa utilizada para comparación

Temporal Evolution of the Migration-related Topics on Social Media?

This poster focuses on capturing the temporal evolution of migration-related topics on relevant tweets. It uses Dynamic Embedded Topic Model (DETM) as a learning algorithm to perform a quantitative and qualitative analysis of these emerging topics. TweetsKB is extended with the extracted Twitter dataset along with the results of DETM which considers temporality. These results are then further analyzed and visualized. It reveals that the trajectories of the migration-related topics are in agreement with historical events

Using Semantic Web technologies in the development of data warehouses: A systematic mapping

The exploration and use of Semantic Web technologies have attracted considerable attention from researchers examining data warehouse (DW) development. However, the impact of this research and the maturity level of its results are still unclear. The objective of this study is to examine recently published research articles that take into account the use of Semantic Web technologies in the DW arena with the intention of summarizing their results, classifying their contributions to the field according to publication type, evaluating the maturity level of the results, and identifying future research challenges. Three main conclusions were derived from this study: (a) there is a major technological gap that inhibits the wide adoption of Semantic Web technologies in the business domain;(b) there is limited evidence that the results of the analyzed studies are applicable and transferable to industrial use; and (c) interest in researching the relationship between DWs and Semantic Web has decreased because new paradigms, such as linked open data, have attracted the interest of researchers.This study was supported by the Universidad de La Frontera, Chile, PROY. DI15-0020. Universidad de la Frontera, Chile, Grant Numbers: DI15-0020 and DI17-0043

Inmunolocalización de receptores de estrógenos acoplados a proteína g en placentas porcinas.

En la gestación porcina, las hormonas esteroideas Estrógenos y Progesterona interaccionan con receptores nucleares y de membrana. El propósito de esta investigación fue determinar la distribución y localización del receptor de estrógenos acoplado a proteína G (GPER) en placentas porcinas de diversos periodos de gestación. Se utilizaron cerdas mestizas gestantes (G) de 15-17 días de gestación (dg) (n= 4), de 30-35 dg (n= 4) y de 60-70 dg (n= 4), provenientes de frigoríficos de la zona de General Pico, La Pampa. Y cerdas no gestantes (NG) (n=4). De cada muestra se realizó una tinción de Hematoxilina/Eosina para determinar la integridad de los tejidos, y posteriormente se realizó la determinación de los receptores de estrógenos por la técnica de inmunoperoxidasa indirecta LSAB (Labelled Streptavidin Biotin). Los resultados de la técnica de inmunomarcación para la determinación de receptores de hormonas esteroideas, se expresaron en forma cualitativa. Se evaluó la expresión según la coloración detectada (diferentes intensidades de marrón). En todos los períodos estudiados se observó inmunomarcación de GPER en células trofoblásticas. En el componente materno se expresó en epitelio luminal y glandular además de músculo liso. Los resultados de este estudio confirman la localización de GPER en endometrio de placentas porcinas de 5, 17, 30 y 70 dg y en células trofoblásticas de 17, 30 y 70 dg. La expresión de los receptores de estrógenos de membrana acuerda con estudios previos en los cuales se cuantificó los niveles de estrógenos en sueros y en el componente materno y fetal de similares etapas de la gestación. Sugerimos que en la interfase materno fetal, los estrógenos podrían ligarse a GPER y establecer vías de señalización específicamente reguladas. Esa comunicación entre la hembra y sus conceptus permitiría inducir y sostener la expresión de moléculas que modulan la implantación, el desarrollo y el mantenimiento de la gestació

Metallic ions as therapeutic agents in tissue engineering scaffolds: an overview of their biological applications and strategies for new developments

This article provides an overview on the application of metallic ions in the fields of regenerative medicine and tissue engineering, focusing on their therapeutic applications and the need to design strategies for controlling the release of loaded ions from biomaterial scaffolds. A detailed summary of relevant metallic ions with potential use in tissue engineering approaches is presented. Remaining challenges in the field and directions for future research efforts with focus on the key variables needed to be taken into account when considering the controlled release of metallic ions in tissue engineering therapeutics are also highlighted